Freedom and moral responsibility have one foot in the practical realm of human affairs and the other in the esoteric realm of fundamental metaphysics—or so we believe. This has been denied, especially in the metaphysics-bashing era occupying the first two-thirds or so of the twentieth century, traces of which linger in the present day. But the reasons for this denial seem to us quite implausible. Certainly, the argument for the general bankruptcy of metaphysics has been soundly discredited. Arguments from Strawson (...) and others that our moral practices are too deeply embedded in human life to rest on anything as tenuous as a metaphysical doctrine far from the thoughts of ordinary people would seem to prove too much: we can easily imagine fantastic scenarios far from the thoughts of ordinary people—involving, say, alien manipulation or massive deception—that, if true, would clearly undermine claims to freedom and responsibility. For still other philosophers, the separation of the moral life from (some) metaphysical issues is prescriptive, not descriptive: it is a recommendation that we revise ordinary moral thought by severing its allegedly problematic links to metaphysics. (Some philosophers appear to hover undecided between such a prescriptive project and a Strawsonian descriptive claim.) We suspect that the prospects of retaining the binding force of ordinary moral thought, were such a reconceived moral practice widely embraced, are bleak. A transition to something closer to moral nihilism seems at least as likely. In any case, our interest here is in descriptive metaphysics, not revisionary. -/- To say as we do that freedom and moral responsibility have a partly metaphysical character is not to suggest that they can be had only if some highly specific version of a particular metaphysical framework is correct. Instead, we suggest in what follows, it is a broadly neo-Humean metaphysics that is not hospitable to freedom (for reasons distinctive to the metaphysics), while a broadly neo-Aristotelian metaphysics is. But we also think (and it is the main aim of our paper to show) that different versions of the neo- Aristotelian metaphysics lead to rather different metaphysical accounts of free and responsible action. Specifically, we will argue that (1) the most satisfactory account of human freedom within the broadly neo-Aristotelian metaphysics is agent-causal, but that (2) two different versions of the general metaphysics will lead to important differences in the agent-causal account of freedom. Adjust the details of your general metaphysics, and the details of your account of freedom are transformed in significant ways. Action theory cannot properly be pursued in isolation from general metaphysics. (shrink)

Federal policies on human subjects research have performed a near‐about face. In the 1970s, policies were motivated chiefly by a belief that subjects needed protection from the harms and risks of research. Now the driving concern is that patients, and the populations they represent, need access to the benefits of research.

This article is based on a public lecture hosted by the Monash University Centre for Human Bioethics in Melbourne, Australia on 11 April 2013. The lecture recording was transcribed by Vicky Ryan; and, the original transcript has been edited — for clarity and brevity — by Vicky Ryan, Michael Selgelid and Jonathan Moreno.

We use concepts of causal powers and their relatives-dispositions, capacities, and abilities-to describe the world around us, both in everyday life and in scientific practice. This volume presents new work on the nature of causal powers, and their connections with other phenomena within metaphysics, philosophy of science, and philosophy of mind.

I explore two accounts of properties within a dispositional essentialist (or causal powers) framework, the pure powers view and the powerful qualities view. I first attempt to clarify precisely what the pure powers view is, and then raise objections to it. I then present the powerful qualities view and, in order to avoid a common misconception, offer a restatement of it that I shall call the truthmaker view. I end by briefly defending the truthmaker view against objections.

Western society today is less unified by a set of core values than ever before. Undoubtedly, the concept of moral consensus is a difficult one in a liberal, democratic and pluralistic society. But it is imperative to avoid a rigid majoritarianism where sensitive personal values are at stake, as in bioethics. Bioethics has become an influential part of public and professional discussions of health care. It has helped frame issues of moral values and medicine as part of a more general (...) effort to find consensus about some of the most perplexing questions of our time. But why is it thought that a moral consensus is important or that it deserves respect? How does moral consensus acquire legitimacy in a society that includes diverse value systems? How is moral consensus possible and how do small groups help create or distort consensus processes? Written by a medical school professor trained in philosophy, this timely work tackles these questions from philosophical, historical, and social scientific standpoints. It begins by describing the traditional ambivalence about consensus in Western culture as well as the uncertain relationship in modernity between consensus and expertise. After outlining the current bioethical consensus, the book gives philosophical and political analyses of the idea of consensus, then assesses the role of consensus in national ethics commissions and in the ethics committee movement. Moreno constructs an original, naturalistic philosophy of moral consensus, referred to as "bioethical naturalism", and then applies sociology and social psychology to actual consensus processes. The book concludes with an account of bioethics as a consensus-oriented social reform movement. This insightful volume will be essential reading for bioethicists, philosophers, physicians, members of ethics committees, and all those concerned with ethical and social issues in health care. (shrink)

The cellular processes of transport, division and, possibly, early development all involve microtubule‐based motors. Recent work shows that, unexpectedly, many of these cellular functions are carried out by different types of kinesin and kinesin‐related motor proteins. The kinesin proteins are a large and rapidly growing family of microtubule‐motor proteins that share a 340‐amino‐acid motor domain. Phylogenetic analysis of the conserved motor domains groups the kinesin proteins into a number of subfamilies, the members of which exhibit a common molecular organization and (...) related functions. The kinesin proteins that belong to different subfamilies differ in their rates and polarity of movement along microtubules, and probably in the particles/organelles that they transport. The kinesins arose early in eukaryotic evolution and gene duplication has allowed functional specialization to occur, resulting in a surprisingly large number of different classes of these proteins adapted for intracellular transport of vesicles and organelles, and for assembly and force generation in the meiotic and mitotic spindles. (shrink)

Three claims are widely held and individually plausible, but jointly inconsistent: (1) Negative actions (intentional omissions, refrainments, etc.) are genuine actions; (2) All actions are events; (3) Some, and perhaps all, negative actions aren't events, but absences thereof (when I omit to raise my arm, no omission-event occurs; what happens is just that no arm-raising occurs). Drawing on resources from metaphysics and the philosophy of language, I argue that (3) is false. Negative actions are events, just as ordinary actions are. (...) Moreover, each token negative action is identical to a token positive event, so we can adopt this realist view of negative actions without adding metaphysically negative entities (absences, negative states of affairs) to our ontology. (shrink)

Recent efforts to support state regulation of risky behavior like cigarette smoking, alcohol consumption, driving without seatbelts and riding motorcycles without helmets have focused on economic justifications—the costs to society of the consequences of these activities. However, opponents have successfully argued that the economic burdens of regulation outweigh the social benefits. To reduce the toll on society of these behaviors, we need justification for regulation that asserts the moral primacy of health and the well‐being of the community.

Causal powers, say, an electron’s power to repel other electrons, are had in virtue of having properties. Electrons repel other electrons because they are negatively charged. One’s views about causal powers are shaped by—and shape—one’s views concerning properties, causation, laws of nature and modality. It is no surprise, then, that views about the nature of causal powers are generally embedded into larger, more systematic, metaphysical pictures of the world. This dissertation is an exploration of three systematic metaphysics, Neo-Humeanism, Nomicism and (...) Neo-Aristotelianism. I raise problems for the first two and defend the third. A defense of a systematic metaphysics, I take it, involves appealing to pre-theoretical commitments or intuitions, and theoretical issues such as simplicity or explanatory power. While I think that Neo-Aristotelianism is the most intuitive of the available general metaphysical pictures of the world, these kinds of intuitions do not settle the matter. The most widely held of the alternative pictures, Neo-Humeanism, is accepted in great part because of its theoretical power. In contrast, a systematic Neo-Aristotelian metaphysic is, at best, nascent. The way forward for the Neo-Aristotelian, therefore, is a contribution to an ongoing research program, generating Neo-Aristotelian views of modality, causation and laws of nature from the Neo-Aristotelian understanding of causal powers. The central argument of this dissertation is that such views are defensible, and so the Neo-Aristotelian metaphysic ought to be accepted. (shrink)

Physicians have long tinkered with ways to "improve" the human brain, but as our understanding of that organ's inner workings quickly grows, artificial enhancement is becoming more feasible. Military research is at the forefront of this work, much of it focused on drugs. The goal is to produce a better soldier, but the emerging techniques could just as easily be applied to any individual. The military wants to juice up personnel's brains because the human being is the weakest instrument of (...) warfare. Although for centuries astonishing and terrifying advances have been made in the technology of conflict, soldiers are basically the same. They must eat, sleep, discern friend from foe, heal when wounded, and so forth. The first state actor to build superior fighters will make an enormous leap in the arms race. In the short run, researchers are trying to devise aids that would overcome a person's inherent limitations, such as mental fatigue. Long-term results could lead to individuals everywhere who are tireless, less fearful or even better speakers. (shrink)

Leading scholars debate politically progressive perspectives on bioethics and the implications for society, politics, and science in the twenty-first century.

This volume takes the first step toward building the necessary local bridges.

It is often assumed that, while ordinary actions are events, ‘negative actions’ are absences of events. I claim that a negative action is an ordinary, ‘positive’ event that plays a certain role. I argue that my approach can answer standard objections to the identity of negative actions and positive events.

Consensus is commonly identified as the goal of ethics committee deliberation, but it is not clear what is morally authoritative about consensus. Various problems with the concept of an ethics committee in a health care institution are identified. The problem of consensus is placed in the context of the debate about realism in moral epistemology, and this is shown to be of interest for ethics committees. But further difficulties, such as the fact that consensus at one level of discourse need (...) not imply consensus at another, oblige us to look more closely at the deliberative process itself. That yields two complementary methods of deliberation that have proven their worth. Finally, placing ethics committees in the context of Dewey's philosophy of social intelligence suggests that consensus should be regarded primarily as a condition rather than as the goal of inquiry. Keywords: ethics committee, consensus, moral authority CiteULike Connotea Del.icio.us What's this? (shrink)

The notion of essence in psychology is examined from a constructivist viewpoint. The constructivist position is summarized and differentiated from social constructionism, after which constructs are distinguished from concepts in order to position ontology and epistemology as modes of construing. After situating constructivism in relation to philosophical approaches to essences, the distinction between essences and kinds is examined and the presumed constructivist critique of essences in psychology outlined. It is argued that criticizing constructivism as an “anything goes” form of antirealism (...) fails to grasp how constructivist psychology, by emphasizing structure and viability, does indeed place limits on the constructions people may hold. In applying a constructivist understanding of essences in general to those fundamental to human psychology, people can be seen as having three essential psychological qualities: they are closed systems, active meaning-makers, and irreducibly social beings. Yet a constructivist view also maintains that these psychological essences only hold while operating within and committed to a constructivist perspective. In other words, what counts as an essence always depends on one's assumptions, or how one construes events. Finally, a personal construct theory model of essentialist and nonessentialist construing is introduced based on the assumption that everyone construes in both essentialist and nonessentialist ways at different times because doing so is pragmatically viable. 2012 APA, all rights reserved). (shrink)

When asked why he turned from philosophy to the history of ideas, Isaiah Berlin said that he was worried that if he stayed in philosophy he wouldn't know any more at the end of his life than he had at the beginning. Mark Lilla makes the point in a somewhat more constructive way: "His [Berlin's] instinct told him that you learn more about an idea as an idea when you know something about its genesis and understand why certain people found (...) it compelling and were spurred to action by it".It took me decades longer than the brilliant Oxford don to appreciate the point, but when I did it came as a lightning strike of recognition. My brain seems to have been keyed from the beginning in the syntax of... (shrink)

I defend the thesis that Composition Entails Identity (CEI): that is, a whole is identical to all of its parts, taken together. CEI seems to be inconsistent, since it seems to require that the parts of a whole possess incompatible number properties (for instance, being one thing and being many things). I show that these number properties are, in fact, compatible.

Recently Trent Dougherty has claimed that there is a tension between skeptical theism and common sense epistemology—that the more plausible one of these views is, the less plausible the other is. In this paper I explain Dougherty’s argument and develop an account of defeaters which removes the alleged tension between skeptical theism and common sense epistemology.

Introduces and reflects upon the major themes of Jewish life as expressed in a full year of holidays in the Jewish calendar.

Convinced that armed conflict with the Soviet Union was all but inevitable, that such conflict would involve unconventional atomic, biological, and chemical warfare, and that research with human subjects was essential to respond to the threat, in the early 1950s the U.S. Department of Defense promulgated a policy governing human experimentation based on the Nuremberg Code. Yet the policymaking process focused on the abstract issue of whether human experiments should go forward at all, ignoring the reality of humans subjects research (...) already under way and leaving unanswered ethical questions about how to conduct such research. Documents newly released to the Advisory Committee on Human Radiation Experiments tell the story of the Pentagon policy. (shrink)